Synthetic strategies of phosphonodepsipeptides

• Jiaxi Xu

Beilstein J. Org. Chem. 2021, 17, 461–484, doi:10.3762/bjoc.17.41

• -hydroxyisovaleric acid-derived spirophosphoranes as the phosphorus reagents [57]. By using a similar strategy, linker-linked bisphosphonodepsidipeptides were synthesized [10]. The current method is also an interesting synthetic strategy of phosphonodepsipeptides. It can realize an asymmetric synthesis of

Copper-catalyzed O-alkenylation of phosphonates

• Nuria Vázquez-Galiñanes,
• Mariña Andón-Rodríguez,
• Patricia Gómez-Roibás and
• Martín Fañanás-Mastral

Beilstein J. Org. Chem. 2020, 16, 611–615, doi:10.3762/bjoc.16.56

• subject to selectivity problems, involve toxic and hazardous materials or are limited to the restricted availability of the corresponding phosphorus reagents. Therefore, the development of alternative methods for the synthesis of acyclic enol phosphonates is highly desirable. Diaryliodonium and aryl

CF₃SO₂X (X = Na, Cl) as reagents for trifluoromethylation, trifluoromethylsulfenyl-, -sulfinyl- and -sulfonylation. Part 1: Use of CF₃SO₂Na

• Hélène Guyon,
• Hélène Chachignon and
• Dominique Cahard

Beilstein J. Org. Chem. 2017, 13, 2764–2799, doi:10.3762/bjoc.13.272

Multicomponent reactions: A simple and efficient route to heterocyclic phosphonates

• Mohammad Haji

Beilstein J. Org. Chem. 2016, 12, 1269–1301, doi:10.3762/bjoc.12.121

• . As shown in this review, they play an important role in organophosphorus chemistry where phosphorus reagents are used as substrates for the synthesis of a wide range of phosphorylated heterocycles. In this article, an overview about multicomponent reactions used for the synthesis of heterocyclic

• compounds bearing a phosphonate group on the ring is given. Keywords: multicomponent reactions; organophosphorus chemistry; phosphorus reagents; phosphorylated heterocycles; Introduction Heterocyclic rings are found in many naturally occurring compounds and they compose the core structures of many

• more than three quarters dealt with the synthesis of new heterocyclic phosphonates from non-heterocyclic phosphorus reagents. The remaining works reported the phosphorylation of parent heterocyclic systems. It is worth mentioning, that most of the cited publications focused on the synthesis of five and

Synthesis and quantitative structure–activity relationship study of substituted imidazophosphor ester based tetrazolo[1,5-b]pyridazines as antinociceptive/anti-inflammatory agents

• Wafaa M. Abdou,
• Neven A. Ganoub and
• Eman Sabry

Beilstein J. Org. Chem. 2013, 9, 1730–1736, doi:10.3762/bjoc.9.199

• -diazidopyridazine reacts with nucleophilic phosphorus reagents, HE reactants, mainly in the tetrazole-form leading to the formation of tetrazolopyridazino-imidazophosphor esters or β-enaminophosphor esters. Biological assays Based on previous reports [24][25][26] that recognized the pyridazine nucleus is being